Sequences of two mutated cDNAs generated with the primer-sets a-K474R and a-R476K using the double-primer PCR method. The primer sets are listed in Table 1. The mutated residue and the two neighboring residues are shown on top of the Desoxyribonukleinsäure sequence. For each primer Reihe, the top DNA sequence is the weit verbreitet sequence, and t